Risk of CAC progression for PA trajectory groups
| PA trajectory groups | No events/total | Model 1 | P value | Model 2 | P value | Model 3 | P value | Model 4 | P value |
| Low | 321/1332 | Reference | 1.0 | Reference | 1.0 | Reference | 1.0 | Reference | 1.0 |
| Moderate | 235/919 | 1.02 (0.87–1.21) | 0.783 | 1.08 (0.91–1.29) | 0.375 | 1.11 (0.91–1.35) | 0.322 | 1.15 (0.94–1.40) | 0.185 |
| High | 84/246 | 1.39 (1.10–1.77) | 0.007 | 1.51 (1.18–1.94) | 0.001 | 1.58 (1.14–2.19) | 0.006 | 1.72 (1.23–2.39) | 0.001 |
Model 1: Unadjusted.
Model 2: Adjusted for baseline age, alcohol consumption, antihypertensive medication use, body mass index, diabetes, education level, low-density lipoprotein cholesterol, race, serum creatinine, systolic blood pressure and smoking status.
Model 3: Adjusted for model 2 covariates plus PA score at year 0.
Model 4: Adjusted for model 2 covariates plus PA score at year 15.
CAC, coronary artery calcium; PA, physical activity.